Normal pressure hydrocephalus (NPH) is often misdiagnosed. It’s often missed entirely. But when it’s detected early and treated appropriately with the placement of a shunt, something remarkable happens: patients can get better – dramatically better.
The data tells a story few people know. And with X-Pressure’s XP One system, that story is poised to become the new standard of care.
Recovery Is Possible – and It’s Happening
While many patients with NPH are left to decline under incorrect diagnoses like Alzheimer’s or Parkinson’s, those who receive proper testing and shunting can experience something far more hopeful.
- Sophytoul Study, CHU Toulouse (2021): Over an 8-year period, 325 patients underwent CSF infusion testing followed by shunt placement. The result? 90% saw improvement in symptoms, with 5+ years of preserved autonomy.
- NICE Study (2008): In another study cited by the UK’s National Institute for Health and Clinical Excellence, 92% of patients with CSF outflow resistance measuring over 18 mmHg/ml/min during infusion testing improved after being shunted.
This is more than data. It’s a call to action.
Why Early, Accurate Detection Matters
NPH affects an estimated 5% of adults over 65 – yet up to 80% of cases go undiagnosed. Why? Because the symptoms (gait disturbance, incontinence, cognitive decline) overlap with those of common neurodegenerative conditions or are brushed off as “just aging.”
CSF infusion testing changes that. By evaluating resistance to cerebrospinal fluid (CSF) outflow, it provides a dynamic picture of brain function that static imaging can’t. It confirms whether a patient is likely to benefit from a shunt – before irreversible damage sets in.
But until now, this test has been difficult to access, inconsistently performed, and reserved for specialized centers. Enter X-Pressure.
From Data to Detection: The XP One Advantage
XP One is transforming CSF infusion testing from a specialized procedure into a streamlined, 20-minute outpatient diagnostic available at the bedside:
- A flushless, auto-calibrating sensor means it works with any lumbar puncture needle — no extra setup, no additional training.
- Real-time CSF outflow resistance data delivered in-app ensures decisions are based on live dynamics, not guesswork.
- 25+ years of multi-center data power our proprietary algorithms, standardizing interpretation across institutions.
- Tablet and smartphone integration brings results directly to the clinician – no delays, no silos.
XP One doesn’t just simplify CSF infusion testing. It standardizes it. And that standardization means more patients — in more places — can finally access the care they need.
When NPH Is Treated, Lives Improve
The potential impact is staggering. For every patient correctly identified and shunted thanks to infusion testing, there’s a future rewritten:
- A fall avoided.
- A memory recovered.
- A care home stay postponed or prevented.
And with tools like XP One, these outcomes don’t have to be rare success stories. They can become expected results.
X-Pressure: Turning Possibility Into Protocol
We believe in a future where NPH is detected early, accurately, and consistently – no matter the setting. XP One is how we get there.
By bringing CSF infusion testing into the everyday workflow, we’re not just improving diagnostic precision. We’re rewriting what’s possible for patients everywhere.
Ready to Bring XP One to Your Clinic?
Reach out to us at contact@x-pressure.com to learn how XP One can help your team deliver earlier NPH detection and better outcomes for more patients.
