Diagnosing normal pressure hydrocephalus (NPH) has long felt like a guessing game — its symptoms vague, its imaging inconclusive, and its outcomes uncertain. But that’s changing. Cerebrospinal fluid (CSF) infusion testing has the power to reshape the diagnostic landscape, offering clinicians clear, measurable insights into CSF dynamics and helping distinguish NPH from other conditions with confidence.
With XP One, X-Pressure brings this game-changing technology directly to the bedside — delivering real-time data, streamlining NPH detection, and empowering providers to make faster, more accurate decisions for patients who can’t afford to wait.
What Is CSF Infusion Testing?
CSF infusion testing evaluates the dynamics of cerebrospinal fluid within the central nervous system. By infusing fluid into the lumbar subarachnoid space and monitoring the resulting pressure changes, clinicians can assess:
- CSF outflow resistance (Rout): Indicates how easily CSF exits the cranial cavity.
- Brain elastance: Reflects the brain’s ability to accommodate CSF volume changes without significant pressure increases.
- Pulsatility index: Measures the variations in intracranial pressure with each heartbeat.
Elevated Rout values are often indicative of NPH and can only be evaluated using a CSF infusion test, thereby providing critical information beyond what imaging studies can offer.
How XP One Makes CSF Infusion Testing More Accessible
Traditional CSF infusion testing methods are cumbersome and often confined to specialized centers. X-Pressure’s XP One system revolutionizes this process by:
- Simplifying the procedure: CSF infusion testing with XP One is a 20 minute, outpatient procedure that replaces the need to perform risky alternate diagnostic procedures, such as external ventricular drainage.
- Enhancing usability: Allowing bedside testing with flushless, auto-calibrating tools.
- Providing real-time data: Offering immediate insights into CSF dynamics to inform clinical decisions based on 25+ years of multi-center data.
Clinical Impact: More Than Just Data
Utilizing CSF infusion testing in the diagnostic pathway of NPH has been associated with improved patient selection for shunt surgery, leading to better postoperative outcomes. Patients accurately diagnosed with NPH and subsequently shunted experience significant symptom improvement.
The Future of NPH Detection Is Here
For too long, patients with NPH have slipped through the cracks and have been misdiagnosed and misinformed. We’re here to change that.
With XP One, we’re ushering in a new era of early detection and smarter intervention, turning delayed diagnoses into life-changing recoveries. The future of NPH detection has arrived — and it’s happening at the bedside.
